A simple method for constructing microinjectrodes for reversible inactivation in behaving monkeys.

نویسندگان

  • L L Chen
  • L Goffart
  • D L Sparks
چکیده

A method for constructing a simple, durable injection-microelectrode (injectrode) is described. The injectrode can record neuronal activity, stimulate neuronal tissues, or inject substances locally through its tip. The injectrode is lightweight and is easy to construct from commercially available parts, and it can be used repeatedly for multiple recordings and injections. Since dura penetration can damage fragile electrode tips, a reliable method to pass the injectrode through an intact dura matter is described.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

The effect of reversible inactivation of the central amygdaloid nucleus on cardiovascular responses in rats with renal hypertension

The brain rennin-angiotensin system (RAS) has an important role in the regulation of cardiovascular function. The aim of the present study was to determine the effect of reversible inactivation of the central amygdaloid nucleus (Ace) in normotensive rats and rats with renal hypertension (2K-1C). Two groups of normotensive rats were selected for this study. In one group, hypertension was induced...

متن کامل

The effect of reversible inactivation of the central amygdaloid nucleus on cardiovascular responses in rats with renal hypertension

The brain rennin-angiotensin system (RAS) has an important role in the regulation of cardiovascular function. The aim of the present study was to determine the effect of reversible inactivation of the central amygdaloid nucleus (Ace) in normotensive rats and rats with renal hypertension (2K-1C). Two groups of normotensive rats were selected for this study. In one group, hypertension was induced...

متن کامل

Effect of reversible inactivation of locus ceruleus on naloxone-induced withdrawal syndrome in paragigantocellular neurons in morphine-dependent rats

In this study, the effect of reversible inactivation of locus ceruleus (LC) on naloxone- induced withdrawal syndrome in paragigantocellular (PGi) neurons in morphine- dependent rats was investigated. For inactivation of LC, 1 µl of lidocaine (2%) was used and for induction of withdrawal syndrome, naloxone hydrochloride (2 mg/kg) was injected systemically. The results showed that in dependent gr...

متن کامل

The effect of reversible inactivation of raphe nuclus on learning and memory in rats

The role of raphe nucleus (R.N) and serotonin in some behaviors such as sleep, cognition, mood, and memory has previously been reported. The median raphe (MR) nucleus is a major serotonin-containing cell group within the brainstem and is one of the main sources of projections to the septum and hippocampus. The hippocampus is widely believed to be essential for context-conditioning learning. Mor...

متن کامل

The effect of reversible inactivation of raphe nuclus on learning and memory in rats

The role of raphe nucleus (R.N) and serotonin in some behaviors such as sleep, cognition, mood, and memory has previously been reported. The median raphe (MR) nucleus is a major serotonin-containing cell group within the brainstem and is one of the main sources of projections to the septum and hippocampus. The hippocampus is widely believed to be essential for context-conditioning learning. Mor...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Journal of neuroscience methods

دوره 107 1-2  شماره 

صفحات  -

تاریخ انتشار 2001